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Michal Hocek Selected Research

Neoplasms (Cancer)

10/2022Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists.
10/2020Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides.
1/2020Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides.
10/2018Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
11/2017Pyrrolo[2,3-d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides.
1/2017Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.
1/2011Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides.
1/20106-(Het)aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents.

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Michal Hocek Research Topics

Disease

8Neoplasms (Cancer)
10/2022 - 01/2010
2Leukemia
01/2020 - 01/2017
1Osteoporosis
08/2023
1Bites and Stings (Sting)
10/2022
1Dengue (Dengue Fever)
12/2021
1Tick-Borne Encephalitis (Encephalitis, Tick Borne)
12/2021
1Herpes Simplex
11/2009

Drug/Important Bio-Agent (IBA)

4Cytostatic AgentsIBA
10/2018 - 01/2010
3NucleosidesIBA
08/2023 - 01/2010
3Antiviral Agents (Antivirals)IBA
12/2021 - 01/2017
27-deazapurineIBA
10/2022 - 01/2017
2RibonucleosidesIBA
12/2021 - 01/2017
2ProdrugsIBA
12/2021 - 01/2011
1ferroceneIBA
08/2023
1Recombinases (Recombinase)IBA
08/2023
1LigandsIBA
10/2022
1InterferonsIBA
10/2022
17-deazaadenineIBA
12/2021
1EstersIBA
12/2021
1Pyrimidine NucleosidesIBA
10/2020
1RNA (Ribonucleic Acid)IBA
11/2017
1DNA (Deoxyribonucleic Acid)IBA
11/2017
1PyrimidinesIBA
01/2017
1Clofarabine (Clolar)FDA Link
01/2010
1DNA Primase (Primase)IBA
11/2009

Therapy/Procedure

1Immunotherapy
10/2022